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1. Berardi M, Attimonelli M, Cascione I, Santamaria M, Accetturo M, Lascaro D, Berardi M, Ceci M, Loglisci C, Malerba D A data mining approach to retrieve mitochondrial variability data associated to clinical phenotypes Meeting: BITS 2005 - Year: 2005 Full text in a new tab Topic: Unspecified Abstract: The maintenance of biological databases is at present a problem of great interest since the progress made in many experimental procedures has led to an ever increasing amount of data. These data need to be structured and stored in databases and made accessible to the biological community in user-friendly ways. Although both the interest and the need of accessing biological databases are high, the mechanisms to fund their maintenance are unclear. Funding agencies cannot support data annotation in terms of labour costs and hence the development of new tools based on “data miming” technologies could greatly contribute to keep biological databases updated. Here we present a new approach aimed to contribute to the annotation in the HmtDB resource (http://www.hmdb.uniba.it/) of variability data associated to clinical phenotypes [1]. These data are prevalently available in literature where they are reported in a completely free style. Thus, we suggest the construction of a knowledge base derived from browsing papers on web and to be used in the retrieval phase. Nevertheless, problems in extracting data from literature come not only from the heterogeneity of presentation styles but mainly from the unstructured format (i.e. the natural language) in which they are represented. In this scenario, the goal is to feed a knowledge base by identifying occurrences of specific biological entities and their features as well as the particular method and experimental setting of the scientific study adopted in the publication. In this work, we describe some solutions to the problem of structuring information contained in scientific literature in digital (i.e., pdf) or paper format. |
2. Berardi M, Malerba D, Marinelli C, Leo P, Loglisci C, Scioscia G A text-mining application able to mine association rules from biomedical texts Meeting: BITS 2005 - Year: 2005 Full text in a new tab Topic: Unspecified Abstract: Collecting, analyzing and extracting useful information from a very large amount of biomedical texts is a difficult task for researchers in biomedicine who need to keep up with scientific advances. Nowadays several domains in medical practice, drug development, and health care require support for such actives such as bioinformatics, medical informatics, clinical genomics, and many other sectors. Moreover, for this particular task, the data to be examined (i.e. textual data) are generally unstructured as in the case of Medline abstracts and the available resources (e.g. PubMed) and as many other textual resources such as medical records, patents etc. and they do not still provide adequate mechanisms for retrieving the required information as well as to help humans in “deeply analyse” very large amount of content. In this work we present a Text-Mining framework aiming to support biomedical researchers in the task of disease-genes relationships identification from scientific abstracts retrieved by querying Medline. |
3. Ceci M, Loglisci C, Salvemini E, Grillo G, D'Elia D, Malerba D Mining spatial association rules of multiple co-occurring motifs to discover cis-regulatory modules Meeting: Proceedings of BITS 2010 Meeting - Year: 2010 Full text in a new tab Topic: Transcriptomics Abstract: Missing |
4. Logisci C, Salvemini E, Turi A, Grillo G, Malerba D, D’Elia D Discovering Relational Association Rules for the Characterization of UTR cis-regulatory modules Meeting: BITS 2009 - Year: 2009 Full text in a new tab Topic: Transcriptomics Gene Expression and Microarray Analysis Abstract: Missing |